Diphenhydramine Dosage – Benadryl

Diphenhydramine (Benadryl) Dose Table
Child’s weight (pounds) 18 25 36 54 72 lbs
Liquid 12.5 mg/ 1 teaspoon (tsp) 1/2 3/4 1 1.5 2 tsp
Liquid 12.5 mg/5 milliliters (ml) 2.5 3.75 5.0 7.5 10 ml
Chewable 12.5 mg 1 1.5 2 tablets
Tablets 25 mg ½ 1 1 tablets
Capsules 25 mg 1 1 caps

When to Use. Treatment of allergic reactions, nasal allergies, hives and itching.

Table Notes:

  • AGE LIMITS. For allergies, don’t use under 1 year of age. (Reason: it causes most babies to be sleepy). For colds, not advised at any age. (Reason: no proven benefits). They should be not be given if under 4 years old. If under 6 years, don’t give products with more than one ingredient in them. (Reason: FDA recommendations 10/2008).
  • DOSE. Find the child’s weight in the top row of the dose table. Look below the correct weight for the dose based on the product you have.
  • MEASURE the DOSE. Syringes and droppers are more accurate than teaspoons. If possible, use the syringe or dropper that comes with the medicine. If not, you can get a med syringe at drug stores. If you use a teaspoon, it should be a measuring spoon. (Reason: regular spoons are not reliable.) Keep in mind 1 level teaspoon equals 5 ml and that ½ teaspoon equals 2.5 ml.
  • ADULT DOSE. 50 mg
  • HOW OFTEN. Repeat every 6 hours as needed.
  • CHILDREN’S BENADRYL FASTMELTS. Each fastmelt tablet equals 12.5 mg. They are dosed the same as chewable tablets.

I do not routinely recommend cold medications to infants under TWENTY FOUR months of age.

I do not recommend combination medications such as Tylenol cold or Motrin cold and flu because you often will need cold medications for a longer period of time than you will need a fever reducer.

If you require a fever medication such as Tylenol (acetaminophen) or Motrin/Advil (Ibuprofen) for more than three days, please call the office.

We do not routinely recommend Tylenol for teething. If you feel that your child needs medication for comfort give it at bedtime only.

Decongestants should not be used under 6 years of age according to recent CDC and AAP guidelines.

      Reason 1: Not approved by FDA because dosage not studied in this age range

      Reason 2: Risk of dosage error causing high blood pressure.

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